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reported a decrease in sialic acid and superoxide dismutase (SOD) in unstimulated whole saliva in patients with DM1, and concluded that these lower values could explain the poorer oral hygiene of these patients.16 By contrast, other studies have described greater antioxidant activity in the saliva of patients with DM1 the antioxidant markers being seen to increase in parallel to HbA1c.13,17 In our study, the salivary GSSG/GSH ratio was increased in diabetic patients at the expense of two factors: an increase in GSSG and a decrease in GSH levels

Utreloxastat (PTC857) is an orally active and blood-brain barrier-permeable 15-lipooxygenase inhibitor

Typical primary antioxidants include phenolic compounds, phenolic acids and their derivatives, flavonoids, tocopherols, phospholipids, amino acids, phytic acid, ascorbic acid, sterols and pigments

The activity of methylated and non-methylated selenium species in lymphoma cell lines and primary tumours