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Patient Characteristics Most patients in cohort 1 were female (62.2%), and the mean age was 70.4 years (standard deviation [SD],13.2)

Dosages used in rodent studies range from 10mg/kg/day to 150mg/kg/day [1, 6, 11]

In vitro, 78c (CD38 inh, 0.5 M) also significantly alleviated Ang II-induced VSMC senescence, as shown by the 64.58% reduction in the SA--gal-positive area (Fig

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