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TDP-43 is usually found in the nucleus, but in many cases of ALS it accumulates in the cytoplasm (TDP-43 proteopathy) (Thakur et al

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(4) The researchers applied the peptide in the picomolar to nanomolar range and observed that it may upregulate the proliferation of dermal papilla cells, a specialized fibroblast population that plays a central role in hair follicular biology

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As an example, GSTs protect cellular DNA against oxidative damage that can lead to an increase of DNA mutations or induce DNA damage promoting carcinogenesis 9

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