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Furthermore, Bui et al (71) demonstrated that treatment of intestinal epithelial cells or hepatocytes with SCFAs, particularly butyrate, notably upregulated the expression and activity of 17-hydroxysteroid dehydrogenase and 3-hydroxysteroid dehydrogenase

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Some reports [21, 24, 25] indicated that clinical symptom, cardiac function, and renal function in CHF patients with renal insufficiency were more likely to be ameliorated with L-C treatment

10.2 EPA and DHA Omega-3 PUFA preparations have been tested in large ASCVD outcome studies that, overall, have only provided weak evidence of their benefits in reducing ASCVD risk