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10.2174/1381612823666170207103943 143 YangF.WangA.ZengX.HouC.LiuH.QiaoS

In addition, transforming growth factor-1 (TGF-1), a potent fibrogenic protein, is known to upregulate astrocyte synthesis of proteoglycans causing severe gliosis (Yin et al., 2009

Cancer Stem Cell Enrichment is Associated With Enhancement of Nicotinamide N-Methyltransferase Expression

By engineering antibodies or biologics to engage these receptors, researchers have increased brain uptake while maintaining BBB integrity and minimizing off-target effects
