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Temozolomide nonresponsiveness in aggressive prolactinomas and carcinomas: management and outcomes

According to a 2023 study in Drug and Alcohol Dependence, over 70% of people who stop using prescription stimulants like Adderall report significant fatigue and sleep disturbances during the first week of withdrawal

In that context, it is noteworthy that optimal function of stem cells depends on their highly specialized microenvironment, or niche [30, 31], and SASP factors deleteriously affect stem cells by altering this niche [32, 33]

Urinary aMT6s provides less resolution, but even with 4 h day time/waketime samples and 8 h/oversleep the calculated acrophase is within 30 min of that derived from hourly sampling (193)
