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Check pH:Test your serum's pH with strips or a meter. Aim for 4.55.5. If it's too alkaline, add a tiny amount of citric acid dissolved in a few drops of water. If too acidic, add a minimal amount of sodium hydroxide solution. Retest after each adjustment
Histidine residues that are buried within hydrophobic regions of the protein have poor access to water and therefore exchange very slowly
& Oliver, S
Both groups received treatment over a 52-week period
