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Antibody titers have been shown to wane over time, with some research suggesting that half the vaccinated population may not have detectable titers of neutralizing antibodies to the newly dominant Delta VOC

Blood tests (FBC and CRP) and plain film radiographs can be undertaken as first line investigations, often most useful to exclude other differentials

It reported rapid metabolism and a prototype half-life under 30 minutes, but it did not test an oral tablet, delayed-release capsule, or buccal spray

It has been established that the peptide was prone to hydrolytic cleavage when subjected to oxidative stressors