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On the other hand, chronic sterile inflammation, characterized by aberrant activation of the immune system, enhanced expression of pro-inflammatory cytokines, such as TNF-, IL-1, IL-6 and IL-18, and activation of immune complexes, such as the NLRP3 inflammasome, is now being recognized as a key driver of disease progression in heart failure [156, 157]
doi: 10.3390/life12111910 32 RaheemALiangLZhangGCuiS
greater than 100 million cells/ml is used
