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Inhibition of BATF/JUN transcriptional activity protects against osteoarthritic cartilage destruction
Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway

Caspase 3 staining reveals active apoptosis in the tissue

10.1126/science.284.5423.2174 9 ChenS.ZhuB.YinC.LiuW.HanC.ChenB.et al (2017)
