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This topic is also discussed, with emphasis on development of mGlu 2 positive allosteric modulators (PAMs)
The failure of these treatments to restore function and slow functional disease progression can be traced to their inability to correct the underlying cause of the dysfunction- diminished synaptic connectivity among neurons in the striatum and neuronal loss in the substantia nigra (SN)
10mg) should be used with Q5126 per 1/1/2023
Raehal et al., 2011
