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doi: 10.1371/journal.pone.0037883, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 64

In research settings, it has been observed to increase pigmentation and modulate central pathways influencing libido and appetite

Ethical Concerns: Images that contained identifiable patient information or did not have proper consent were excluded to uphold ethical standards

Toxic Methemoglobinemia Causes Various exogenic chemical agents and drugs directly or indirectly induce the oxidation process: nitrites (used as supplements to food, amyl nitrite, nitroglycerin) nitrates (silver nitrate, bismutum subnitricum, salts) nitrobenzene (perfume and explosives industry) nitrogases (autogenous welding) chlorates (potassium chlorate) analgetics (phenacetin, acetanilide, etc.) sulfonamides aniline derivates (dyes) local anesthetic agents in the amide class