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Targeting chromosome regions to cause bacterial cell death is one pathogen-focused method

370,371 Alignment between the circadian clock and environmental and physiologic cyclesor circadian synchronycan be disturbed by a range of common behaviors and conditions, including shiftwork, late-night social or other activities, and travel through time zones

Several factors contribute to pigmentation including sun exposure that causes sunspots, pollution which leads to discoloration, hormonal changes from pregnancy, birth control or imbalances that can result in melasma

doi: 10.1016/j.cell.2013.12.016 46 DevillardE.McIntoshF