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Once absorbed, NAC must undergo deacetylation to yield cysteine

Neurochem Res 34:19621968 Pong WW, Stouracova R, Frank N, Kraus JP, Eldred WD (2007) Comparative localization of cystathionine beta-synthase and cystathionine gamma-lyase in retina: differences between amphibians and mammals
The compound CC-220 is currently in phase III clinical trials for the treatment of systemic lupus erythematosus and relapsed/refractory multiple myeloma, through the induction of IKZF1 and IKZF3 protein degradation 213
