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Interestingly, Escherichia coli overexpresses this enzyme, and other microbial species that have IsmA genes have been linked to lower blood cholesterol levels (75)
TMAO precursors are biodegraded by gut microbiota to generate pro-inflammatory molecules
Journal of Nutrition and Metabolism, 2016

This disorder is associated with other chronic diseases, such as hypertension, stroke, depression, anxiety, and cardiovascular diseases (2, 5, 6)
