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For PGA, concentrations were calculated from the ratio of endogenous metabolite to isotopically labelled internal standards, compared against calibration curves of increasing endogenous standard concentrations

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Immediate stop: If any mole shows ABCDE changes, discontinue MT-II and see a dermatologist immediately Melanotan 1 vs Melanotan 2: Which to Choose Both compounds stimulate melanin production, but their pharmacological profiles differ significantly

Takano, 2015)