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Thymosin Alpha-1 & Beta-4 Strengthen immune function and speed up tissue regeneration

Funding This work was supported by INOVA FIOCRUZ (VPPCB-005-FIO-20-2-115), Coordenao de Aperfeioamento de Pessoal de Nvel SuperiorCAPES (88881.504749/2020-01

This mechanism has positioned AHK-Cu as a compound of interest for researchers studying skin matrix integrity, structural protein regulation, and age-related changes in connective tissue biology

In contrast, pathways typically linked to cellular protection, including MYC targets V1, protein secretion, DNA repair, oxidative phosphorylation, the unfolded protein response, MTORC1 signaling, and adipogenesis, were markedly downregulated (Figure 4B and Supplemental Figure 6A)