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Reproductive longevity and aging: geroscience approaches to maintain long-term ovarian fitness

98 Disruptions in these processes contribute to GBM aggressiveness and treatment resistance

Simultaneously, low levels of p53 downregulate peroxisome proliferator-activated receptor gamma coactivator 1 (PGC-1), mitochondrial transcription factor A, and p53-induced ribonucleotide reductase M2B subunit to impair mitochondrial function [101]

In: Zhang L, Demain AL (eds) Natural products
