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Description
The crystal structure of the wild-type AR illustrated the reason why the LxxLL motifs of typical NR coactivators fail to hydrogen bond with Glu897 of H12 and make fewer and less optimized hydrophobic contacts with the AF2 pocket compared with FxxLF-containing peptides, explaining the lower affinity of AF2 for the LXXLL-containing p160-type coactivators 82
All es donde complementar una dieta saludable con un suplemento de CLA puede aportar mucho
[22] reported a single instance of ruptured appendix during the trial, though it was deemed to be unrelated to the sulforaphane supplementation
Ehrmann, DA
