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Similar to any other disease, these figures represent only reported cases, and the actual number of individuals affected by breast cancer may be higher, as some cases may go undiagnosed or unreported

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Carnosine regulates the binding of serotonin to its receptor in rat brain [161] and modulates the activity of monoamine oxidase-A in different rat brain regions [162]

Therefore, our findings suggest that pyroptosis of synovial macrophages plays a role in inducing inflammation in synovial chondrocytes and targeting synovial macrophages may be a potential therapeutic strategy for OA management