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47th Annual Meeting Society of Thoracic Surgeons, 2011

While the collapse of the immune privilege is considered as one of the most accepted theories accounting for AA, the exact pathogenesis of this disease remains unclear by now

Mechanistically, KD or KD-induced BHB exerts anti-inflammatory, anti-fibrotic, anti-oxidative stress, and autophagy effects on renal tissues and cells (as illustrated in Fig

Genome-wide analysis showed that H4K12la is enriched at the promoters of glycolytic genes ( PKM2 , Ldha , and Hif-1 ) and activates transcription, thereby increasing glycolytic activity
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