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Currently, the application of metabolomics as a tool for the identification of biomarkers of histamine metabolism in urine is also being challenged as a possible new diagnostic strategy [11]
Timeline expectations based on mechanisms: Gene expression changes (GHK-Cu) occur within days but take weeks translating to measurable functional improvements
Reactive oxygen species (ROS) may play an important role in activation of DCs [52] and increase the DC ability to activate CD4 + T cells [53]
