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[1] [2] B12 functions as a cofactor in cellular metabolism, participating in the conversion of homocysteine to methionine and the metabolism of methylmalonic acid, both crucial for energy production

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The possibility of intersystem crossing, and the formation of triplet RPs is also discussed based on Landau-Zener theory

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Biochemically, the cobalt center can take part in both two-electron and one-electron reductive processes to access the "reduced" (B 12r , +2 oxidation state) and "super-reduced" (B 12s , +1 oxidation state) forms

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It is commonly used to improve body fat distribution and assist in weight management

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