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After its conversion to acetyl-CoA , for example, pyruvate may serve as a precursor for fatty acid biosynthesis or for the synthesis of the amino acid alanine

This means that working on cancer cells alone will not achieve the goal of completely eliminating the tumor and new treatment strategies should consider the TME, that is, the surrounding immune cell components

Puerarin attenuates LPS-induced inflammatory injury in gastric epithelial cells by repressing NLRP3 inflammasome-mediated apoptosis

2.6 UPLC-Q-TOF/MS analysis Separation was completed using a Thermo ScientificTM ultrahigh-performance liquid chromatography (UPLC) system (Thermo, San Jose, CA, USA)