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Moreover, the combined loss of the FGF2 and FGF6 genes increases the dystrophic pathology in the musculature of mdx mice, whereas the transgenic delivery of both factors to damaged muscle enhances regeneration [79, 80]
A targeting vector in which the gene of interest has been disrupted is introduced into the genome of a mouse embryonic stem cell by homologous recombination

However, during phagocytosis, the contents of neutrophil granules may be released into the extracellular environment, particularly hydrolytic enzymes released by lysosomes

J.MichelH.et al (2007)
