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Recent studies have demonstrated that in the bilateral carotid artery stenosis (BCAS) mouse model of chronic cerebral ischemia, sham-operated controls were used for comparison, and a significant increase in GFAP + astrocytes was observed within 28 days after surgery (45)

Population studies indicate increased systemic oxidative stress biomarkers in hypertensive patients, correlating oxidative stress with a higher risk of hypertension even in normotensive individuals [247]

"Increased Concentrations of Homocysteine in the Cerebrospinal Fluid in Patients with Fibromyalgia and Chronic Fatigue Syndrome"

Gut ischemia/reperfusion induced acute lung injury is an alveolar macrophage dependent event
