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Overview Designed as a practical, awareness-raising guide for the clinician Provides key information relevant to the diagnosis and management of each primary immunodeficiency (PID) Comprises a series of case-oriented problems drawn from typical patient scenarios Enables prompt recognition of PIDs, thereby helping to avoid delayed diagnosis and its consequences Includes supplementary material: sn.pub/extras Includes supplementary material: sn.pub/extras Access this book Tax calculation will be finalised at checkout Other ways to access About this book Primary immunodeficiency diseases (PIDs) are a heterogeneous group of inherited disorders characterized by different defects in the development and function of the immune system

USA 101 , 37803785 (2004)

Lipopolysaccharide-induced increase in intestinal epithelial tight permeability is mediated by Toll-like receptor 4/myeloid differentiation primary response 88 (Myd88) activation of myosin light chain kinase expression