l-carnitine safety in pregnancy Vitamin Supplement for Energy and Metabolism Boost Maternal Dietary L-Carnitine Supplementation Influences

For example, C16-carnitine (10 M) may impair mitochondrial function in rat ventricular myocytes by accelerating ROS production and increasing the probability of mitochondrial permeability transition pore (mPTP) opening, whereas low concentrations (1 and 5 M) of C16-carnitine lightly hyperpolarize the m but do not open the mPTP [293]

Too much Cu/Zn-dependent superoxide dismutase may also increase oxidative stress, leading to redox imbalance due to reactions with hydrogen peroxide (H 2 O 2 ) and peroxynitrite [17]

Matsuishi T, Hirata K, Terasawa K et al : Successful carnitine treatment in two siblings having lipid storage myopathy with hypertrophic cardiomyopathy

& Kubo, Y