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Osteoblasts also produce osteoprotegerin, a decoy receptor of RANK-L, thereby counteracting and fine tuning the effect of RANK-L in osteoclastogenesis

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[DOI] [PubMed] [Google Scholar] 21.Nelson DR, Cooper JN, Lalezari JP, et al

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Alternatively, it can be metabolized into -butyrobetaine or betaine (58, 59), with -butyrobetaine further transformed into TMA by YeaW/X (60), enzymes specific to Gammaproteobacteria ( 61)

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However, there is currently no direct evidence demonstrating that topical retinoids clearly have a sebo-suppressive effect

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