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doi: 10.18632/oncotarget.25166 4 Galicia-VzquezGSmithSAloyzR

6 Molecular basis of the thiamine-induced improvements in gastrointestinal disorders As mentioned above, despite the direct exposure of the gastrointestinal system to nutritional supply, this system often exhibits thiamine-responsive dysfunctions even when no known TD signs are evident in other tissues
While the peptide appeared well tolerated in these trials, the absence of reproducible clinical benefit meant the molecule did not progress to approval or further late-stage studies

doi: 10.3389/fphar.2019.01131
