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It has previously been observed that increased GSK-3 expression and activity in cell and mouse models of AD are associated with the upregulation of p-tau at Ser396 and Ser404, accompanied by a high rate of apoptosis [20]

Employing this rat model of HMG-induced lung injury, we observed significant attenuation of the pulmonary injury when experimental animals were complement or neutrophil depleted prior to HMG challenge

Two types of vaccines are under investigation: tumor cell vaccines (composed of actual cancer cells, sometimes the patients own) and antigen-based vaccines (target specific proteins expressed by the tumor cells) (Brahmer 2013)

M.GrabowskiM.PondelN.GrabowskaK.et al (2021)