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[3] Because MK-677 activates the ghrelin receptor, it is accurately described as a ghrelin receptor agonist or ghrelin mimetic. At the cellular level, GHSR1a is a Gq-coupled receptor: activation drives phospholipase C, inositol trisphosphate, and a rise in intracellular calcium in pituitary somatotrophs, which triggers GH release

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Cell Stem Cell 7, 470482

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Mice were anesthetized with isoflurane and fixed in prone position

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MicroRNA-216a inhibits neuronal apoptosis in a cellular Parkinsons disease model by targeting Bax

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