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[DOI] [PubMed] [Google Scholar] 24.Stephens F.B., Constantin-Teodosiu D., Laithwaite D., Simpson E.J., Greenhaff P.L

Statistics show that LOX gene mutations are the second most common cause of ARCI (Krieg and Furstenberger, 2014)

Therefore, the designed mitochondrion-targeting nanoparticle can improve mitochondrial enrichment of Fe-ISAzyme and mitochondrial number, which is beneficial to maximize their therapeutic effect