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Description
Without adequate B12, these processes begin to function sub-optimally and the effects, while not always dramatic in the early stages, accumulate in ways that many people experience as persistent tiredness, reduced mental sharpness, lower mood and a general lack of the vitality they feel they should have

Iranian journal of basic medical sciences

This depends on your individual needs

Use an insulated travel case with gel ice packs to maintain 2-8 degrees Celsius
