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Macrophage action, chemokine CCL2 (C-C motif ligand 2), and neuroinflammation have a positive effect in regeneration (Zigmond and Echevarria, 2019)

Blood testing may be recommended where deficiency is suspected

3 Interactions of autophagy with the cGAS-STING pathway 3.1 cGAS The interplay between autophagy and cGAS occurs through (i) cGAS-Beclin-1 interaction that promotes autophagic degradation of cytosolic dsDNA, (ii) cGAS-LC3 interaction that promotes micronucleophagy, and (iii) degradation of cGAS through p62-mediated selective autophagy ( Figure 3 )
[DOI] [PMC free article] [PubMed] [Google Scholar] 186.Martinez-Outschoorn U.E., Peiris-Pages M., Pestell R.G., Sotgia F., Lisanti M.P
