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The free radical theory of aging proposes that the damage from oxidative stress plays a key role in age-related diseases ( Magnetic resonance spectroscopy (MRS) studies show that older individuals have lower GSH levels in the posterior cingulate and occipital cortices ( Some studies in older adults addressed the relationship between GSH levels and general cognitive integrity and found a null association between cognitive integrity and GSH levels in the cingulate, occipital, medial frontal, and sensorimotor cortices ( Whereas the above-mentioned studies have addressed the relationship of cognitive integrity with baseline levels of GSH, to our knowledge, it has not been explored whether GSH is modulated (showing a decrease or increase) as a consequence of cognitive effort (active engagement in a cognitive process) or sustained cognitive effort (continued engagement during a prolonged period)

doi: 10.1007/s10753-020-01338-2 10 StockwellBR

While it does not directly stimulate collagen creation (like vitamin C or retinoids do), its cleansing and antioxidant effects assist the skin in maintaining a healthy environment