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The follow-up that matters for this specific compound landed in 2018, when a small-molecule NNMT inhibitor was given to obese mice

However, studies examining effects of both glutamine and glutamate demonstrated differential effects of these FAAs on functions of IECs and intestinal morphology

The mechanisms of tissue damage in this disease are not fully understood, although it is believed that increased intracellular cystine leads to alteration of GSH levels (Levtchenko et al., 2005)

1 Introduction Sjgrens syndrome (SS) or Sjgrens disease (SjD) is an autoimmune disease that primarily causes dryness of the exocrine glands, in which the salivary and lacrimal glands are predominantly affected