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4 This cell death signaling process involves the activation of different signaling cascades such as apoptosis signal-regulating kinase 1 (ASK1), poly (ADP-ribose) polymerase (PARP), and autophagy-related (ATG) 4 (ATG4) by ROS

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FIGURE 2 7 Molecular alteration and dysregulation pathways in EC: distinction between endometrioid EC and serous EC Endometrial endometrioid carcinomas (EECs) are marked by frequent genetic mutations and pathway dysregulations that drive their development and progression (60)

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