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Treatment of the BV2 cell line with -synuclein increases the secretion of exovesicles expressing the MHC Class II and TNF- molecules on the surface as well as inducing neuronal apoptosis (Chang et al., 2013)
Morrow et al., 2007)
At the molecular level, their phenolic hydroxyl groups readily donate hydrogen atoms to neutralize reactive oxygen and nitrogen species, forming relatively stable phenoxyl radicals through resonance delocalization across aromatic rings (9497)
Cynader, Pyruvate Released by Astrocytes Protects Neurons from Copper-Catalyzed Cysteine Neurotoxicity
