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Silymarin may exhibit antioxidant effects by scavenging and preventing the formation of reactive molecules called free radicals that can contribute to cell damage and disease development

Causes and progression factors of liver inflammation Direct damage caused by alcohol metabolites Ethanol metabolism in the liver occurs through three primary pathways: the alcohol dehydrogenase (ADH) pathway in the hepatocyte cytosol, the cytochrome P450 2E1 (CYP2E1) pathway in the endoplasmic reticulum, and the catalase (CAT) pathway in peroxisomes [18]

Data availability The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with the dataset identifier PXD061388

Using B6 as a cofactor, Hcy can also be converted to cysteine via transsulfuration for use in glutathione synthesis [34] (Figure 1)