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While intuitively appealing, this theory is not supported by physiological evidence

doi: 10.1016/0009-8981(93)90114-J 149 BeaudeuxJLGuillausseauPJPeynetJFlourieFAssayagMTielmansDet al

[102] Surgery [edit] If medical treatment is not effective, surgery may be performed

[63] The specific effects of various noble kavas depend on various factors, such as the cultivar used (and the related specific composition of kavalactones), age of the plant, and method of consumption