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Yet, as we navigate our modern lives, the prevalence of alcohol consumption can complicate our wellness efforts

4.7 Iron Iron concentration is regulated by the hepcidin/ferroportin axis: liver hepcidin binds to tissue ferroportin, causing its internalization, blocking iron export, and therefore lowering serum concentration

Then, strong evidences from Mendelian randomization study [48], systematic review and meta-analysis [6, 9], cohort studies [7], prospective nested case-control study [8], observational studies [11] etc., indicated that elevated iron storage, ferritin, transferrin saturation, iron stores and decreased transferrin levels, is linked to a heightened risk of DM and its complication

Williams J, Holmes RP, Assimos DG, Mitchell T (2016) Monocyte mitochondrial function in calcium oxalate stone formers