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Patients with major depressive disorder showed decreased amplitudes and delayed/advanced phases of the circadian rhythms such as core body temperature and melatonin [58,59,60]

Anecdotal reports describe shorter recovery times and quicker returns to physical activity

However, ethnicity data are more available than race demographics data, as shown in Table B-1

Participants taking the highest dose of orforglipron (36 mg) experienced a mean weight loss of 7.3 kg , or 7.9%, compared with 1.3 kg or 1.6% in the placebo group
