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Description
Gliotoxin can also lead to the reshaping of the actin cytoskeleton [54], thus contributing to cell shrinkage and filopodia disappearance, which can be reversed by Cyclic Adenosine monophosphate (cAMP) antagonist Rp-cAMP
STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca 2+ levels

doi: 10.1186/s13223-018-0278-1

To address this challenge and improve treatment outcomes, there is growing interest in combining EGFR-TKIs with complementary therapeutic strategies, such as TCMs [95, 263, 264]
