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More specifically, while there are large datasets available for training popular methods (e.g., image recognition) where interpolation is often targeted, thousands of datapoints can hardly represent the chemical space estimated at 10 60 9 , and extrapolation is required
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When used with selective serotonin reuptake inhibitors (SSRIs), the combination can increase serotonin levels to dangerous levels, leading to potentially fatal serotonin toxicity
