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Research has not shown that doses above 0.5 mg per day provide meaningfully better results, so there is no benefit to pushing higher

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Complete restriction typically becomes unnecessary as tissues regain baseline capacity

Criner, MD 1 and the COPDGene Investigators Author Affiliations | Correspondence | Abstract | Citation | Keywords | PDF Author Affiliations Department of Pulmonary and Critical Care Medicine, Temple University Hospital, Philadelphia, Pennsylvania Department of Radiology, Temple University Hospital, Philadelphia, Pennsylvania Temple Clinical Research Center, Temple University School of Medicine, Philadelphia, Pennsylvania *Co-first Authors Address correspondence to: Cynthia Kim, MD Temple Lung Center 7th Floor Parkinson Pavilion 3401 North Broad Street Philadelphia, PA 19140 Phone: 267-858-2735 Email: [email protected] Abstract Background: Gastroesophageal reflux disease (GERD) is associated with frequent chronic obstructive pulmonary disease (COPD) exacerbations