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Microbial Pathways in Colonic Sulfur Metabolism and Links with Health and Disease
In AD, plaques of amyloid-beta and neurofibrillary tangles of tau are key pathological hallmarks
This shift results in a net loss of inhibitory tone and a gain of facilitatory drive, effectively removing the brakes on and pressing the accelerator for pain transmission at the spinal level
[PubMed: 19456325] 21
