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While it can be distracting, it is usually not cause for immediate concern
The AOD9604 before and after data from clinical trials shows fat loss of 24% body fat over 12 weeks, with particularly notable reductions in abdominal and visceral adipose tissue

The competition between NAD + salvage and the methylation of NAM suggests that NNMT may reduce the oxidation of fuel and increase the storage of fat by regulating the formation of NAD + (Trammell and Brenner, 2015)
