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doi: 10.1016/j.bbagrm.2021.194734
Old Wistar rats treated with GH showed increased circulating IGF-1 levels and reductions in age-associated oxidative stress in skeletal muscle [23]

Of course, thats much better than the one-shot-every-three-months protocol it later changes to

In particular, the biochemical analysis revealed the accumulation of MMA and alteration of metabolites in vB12-related pathways in the brain of adult Tbx1 +/ mice, and in mice carrying a multigenic deletion ( Df1/ + ) of 22q11.2DS orthologs that includes Tbx1 (19)