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Global Grk4 knockout mice have lower SBP and DBP than Grk4 wild-type (WT) mice [78]

Science 274, 13791383

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Ahyayauch et al., Both A40 and A42 bound to cholesterol-dependent GM1 clusters and underwent a conformational transition from an -helix-rich structure to a -sheet-rich amyloidogenic conformation, but it was 10-fold more significant for A42 than for A40 (Matsuzaki, 2011
